Examination of allergen-specific upregulation of thymic stromal lymphopoietin receptor on basophils from allergic rhinitis patients
Not Applicable
- Conditions
- allergic rhinitis
- Registration Number
- JPRN-UMIN000038378
- Lead Sponsor
- Department of Otorhinolaryngology, Graduate School of Medicine, Chiba University
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 135
Inclusion Criteria
Not provided
Exclusion Criteria
- Severe bronchial asthma or sever atopic dermatitis - Allergic rhinitis possibly caused by dog, cat, cockroach or moth - Specific IgE level of dog, cat, cockroach or moth is higher than house dust mite or higher than 10UA/mL - Received allergen-specific immunotherapy of house dust or house dust mite - Medicated with inhaled corticosteroids within 3 months before blood collection - Received anti-human IgE antibody therapy
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate clinical sensitivity, clinical specificity, positive predictive value and negative predictive value of allergen-specific upregulation of thymic stromal lymphopoietin receptor of basophils
- Secondary Outcome Measures
Name Time Method - ROC analysis and estimate sensitivity, specificity, predictive values with the optimal cutoff