Immunological changes of Immmunotherapy in allergic rhinitis
Phase 2
- Conditions
- Allergic Rhinitis.Perennial allergic rhinitis
- Registration Number
- IRCT2015071623235N1
- Lead Sponsor
- Mashhad University of Medical Sciences, Vice chancellor for research
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 25
Inclusion Criteria
All patients with persistent allergic rhinitis aged 45-10 years; Residence in Mashhad that have positive skin test to the local common aeroallergens and are willing to cooperate in the project.
Exclusion criteria:
Patients with seasonal allergic rhinitis, patients who have a history of autoimmune disease;Patients who consumed steroids or immunosuppressive drugs and effective on immune system; Pregnant women; Patients with immune deficiencies diseases, Patients with allergic asthma; Patients with malnutrition
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Cytokines Variations. Timepoint: Comparison baseline and terminal sample, after one year of treatment course. Method of measurement: Measuring selective cytokines by Real time PCR.
- Secondary Outcome Measures
Name Time Method Systemic reactions to immunotherapy. Timepoint: Each immunotherapy session. Method of measurement: Clinical evaluation.