Phenotype and number of regulatory T cells present in peripheral blood of COPD patients versus healthy controls
- Conditions
- chronic bronchitisCOPDEmphysema1002766510024967
- Registration Number
- NL-OMON30145
- Lead Sponsor
- niversitair Medisch Centrum Groningen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 50
COPD patients
• Clinical diagnosed COPD
• FEV1 < 80% predicted, FEV1/FVC < 70%
• No use of (inhaled) corticosteroids in the 6 weeks preceding the study
• Age > 40
• > 10 pack years
• Ex-smokers have to have quitted smoking for at least one year
• No other health problems
• Informed consent;Healthy controls:
• No signs of pulmonary disease
• No other health problems
• FEV1 > 90 % predicted, FEV1/FVC > 70%
• Age > 40
• Smokers and ex- smokers > 10 pack years
• Never smokers, i.e. no cigarettes last year, and maximal 5 pack years
• Ex-smokers have to have quitted smoking for at least one year
• Informed consent
• Use of (inhaled) corticosteroids in the 6 weeks preceding the study
• Problems with alcohol or drugs
• COPD exacerbation in the 6 weeks preceding the study
Study & Design
- Study Type
- Observational invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method