Assessment of breast lesion size and characterization: correlation of cone-beam breast-CT, digital breast tomosynthesis, full-field digital mammography with histopathological examination of mastectomy specimens
- Conditions
- C50Malignant neoplasm of breast
- Registration Number
- DRKS00012625
- Lead Sponsor
- niversity Medical Center Goettingen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 40
Inclusion Criteria
Patients scheduled for mastectomy due to at least one biopsy-proven malignant breast lesion.
Exclusion Criteria
Age under 18 years and prophylactic mastectomy.
Study & Design
- Study Type
- observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Measurement (in millimeter) of breast lesions by FFDM, DBT and CBBCT immediately after mastectomy via a radiologist. Lesion size was measured in coronary orientation.<br>Immediate histological fixation of the mastectomy specimen, histopathological size measurement of breast lesions (in millimeter) within a few days via a pathologist.
- Secondary Outcome Measures
Name Time Method Characterisation of breast lesions with the aforementioned imaging modalities in comparison to histopathology.