Breast Lesions Characterization on Contrast Enhanced Ultrasound With Histopathological Correlation
Not Applicable
- Conditions
- Malignant Neoplasm, Overlapping Lesion of Breast
- Interventions
- Drug: Sonovue, Bracco
- Registration Number
- NCT02177045
- Lead Sponsor
- Rambam Health Care Campus
- Brief Summary
Breast lesions are a common condition, diagnosed by imaging and palpation. In order to reduce the number of biopsies performed to the definitive diagnosis of a breast lesion, an imaging method with a high degree of accuracy is needed. Ultrasound imaging with microbubbles contrast media allows the diagnosis of vascularization of the lesion, according to timing. Our hypothesis is that a highly vascularized lesion that enhances in an early timing is most likely to represent a malignant lesion and thus, deserves biopsy for a definitive diagnosis. Females over 18 years age, with a focal lesion in breast will be suitable to perform this examination.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 50
Inclusion Criteria
- Female with a diagnosed breast focal lesion
Exclusion Criteria
- Allergic conditions to contrast media,
- asthma,
- R-L shunt
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Arm && Interventions
Group Intervention Description Microbubbles contrast media for US Sonovue, Bracco Sonovue, Bracco, microbubbles contrast media
- Primary Outcome Measures
Name Time Method Tumor vascularization one year
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Ultrasound Unit Imaging Dept Rambam Health Care Campus
🇮🇱Haifa, Israel