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临床试验/NCT05835544
NCT05835544已完成不适用

Acute Responses to High-intensity Interval Exercise (HIIE) and Blood Flow Restriction (BFR)

Nanyang Technological University1 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2022年8月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
1
主要终点
Blood lactate concentration

研究概览

简要总结

The study aims to look at the blood flow restriction (BFR) + high intensity interval training (HIIT) variables to induce an optimal acute training stimulus (i.e., acute responses in main outcome measures of muscular activation, muscular deoxygenation, and secondary outcome measures of heart rate (HR), blood lactate (bLa), subjective ratings of perceived exertion and discomfort)

The hypotheses for this study are: (i) BFR increases muscular deoxygenation, muscular activation when HIIT exercise is of the same intensity, (ii) however, comparing between a lower BFR + HIIT exercise intensity (e.g. 80% V̇O2max) and higher HIIT exercise intensity (e.g. 100% V̇O2max), muscular deoxygenation and activation will be similar but HR will be lower in the BFR + HIIT condition.

详细描述

This study revolves around the optimisation of blood flow restriction (BFR) and high-intensity interval training (HIIT) protocols for the racket sport athlete. The study aims to look at the BFR + HIIT variables to induce an optimal acute training stimulus. This can be achieved with the consideration of two main research questions: (i) What is the ideal combination of BFR cuff pressure and exercise intensity (i.e. cycling) to elicit favourable training stimuli, i.e., acute responses in main outcome measures of muscular activation, muscular deoxygenation, and secondary outcome measures of heart rate (HR), blood lactate (bLa), subjective ratings of perceived exertion and discomfort?; (ii) How does BFR + HIIT compare with traditional HIIT at a similar or higher exercise intensity in terms of these acute responses?

The hypotheses for this study are: (i) BFR increases muscular deoxygenation, muscular activation when HIIT exercise is of the same intensity, (ii) however, comparing between a lower BFR + HIIT exercise intensity (e.g. 80% V̇O2max) and higher HIIT exercise intensity (e.g. 100% V̇O2max), muscular deoxygenation and activation will be similar but HR will be lower in the BFR + HIIT condition.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Crossover
主要目的
Other
盲法
None

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Male
接受健康志愿者
是

入选标准

  • •Age: 18-40 years
  • •Competed in competitive varsity sports (endurance, tennis, badminton, squash, football, basketball, etc.) at the varsity/club level
  • •Actively training for at least 2 sessions (1 - 1.5h) per week
  • •Healthy (free from illnesses) and no musculoskeletal injuries for the past 6 months
  • •No history of cardiometabolic, vascular diseases or similar conditions (high blood pressure, peripheral vascular diseases, heart diseases, metabolic syndrome, diabetes, stroke, etc.).
  • •Pass pre-participation health screening tests - Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and Australian Institute of Sport (AIS) Blood Flow Restriction (BFR) pre-screening questionnaire (no history of any risk factors).
  • •Maximal oxygen uptake (VO2max) of ≥40mmol/min/kg during a maximal aerobic cycling test.
  • •Non-smoker
  • •Drink alcohol less than 3 times each week and less than 3 drinks each time

排除标准

  • •Any diagnosed form of cardiometabolic disease (CVD, diabetes, metabolic syndrome, hypertension)
  • •Any symptoms contraindication of exercise testing (eg chest pains)
  • •Any balance or dizziness problems
  • •Any chronic medical conditions (whether medicated or not)
  • •Any bone joint problems
  • •Any Physician diagnosed contraindications to exercise

研究组 & 干预措施

HIIT Control

Active Comparator

High intensity interval cycling

干预措施: Active Comparator: HIIT Control (Other)

HIIT + BFR between cycling sets

Experimental

High intensity interval cycling with blood flow restriction applied between sets of cycling

干预措施: Experimental: HIIT + BFR between cycling sets (Other)

HIIT + BFR moderate occlusion during cycling

Experimental

High intensity interval cycling with moderate blood flow restriction applied during cycling

干预措施: Experimental: HIIT + BFR moderate occlusion during cycling (Other)

HIIT + BFR high occlusion during cycling

Experimental

High intensity interval cycling with high blood flow restriction applied during cycling

干预措施: Experimental: HIIT + BFR high occlusion during cycling (Other)

结局指标

主要结局

Blood lactate concentration

时间窗: Measured and compared between each acute arm (condition)

Fingertip capillary measure

Muscle oxygenation

时间窗: Measured and compared between each acute arm (condition)

Near infra-red spectroscopy to examine regional tissue (the vastus lateralis muscle) oxygenation i.e, the percentage of haemoglobin and deoxyhaemoglobin (physiological parameter)

Heart rate

时间窗: Measured and compared between each acute arm (condition)

Heart rate using short-range telemetry

Muscle activation

时间窗: Measured and compared between each acute arm (condition)

Surface electromyography of the vastus lateralis and biceps femoris muscles to determine electrical activity of the motor units (physiological parameter)

次要结局

  • Rating of perceived exertion(Measured and compared between each acute arm (condition))
  • Exertion and Pain scale(Measured and compared between each acute arm (condition))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Stephen Burns

Associate Professor

Nanyang Technological University

研究点 (1)

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