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临床试验/NCT05835557
NCT05835557已完成不适用

Physiological Outcomes of High-intensity Interval Training With Post-exercise Blood Flow

Nanyang Technological University1 个研究点 分布在 1 个国家目标入组 40 人开始时间: 2023年7月1日最近更新:
适应症
干预措施

试验速览

阶段
不适用
状态
已完成
入组人数
40
试验地点
1
主要终点
20 km Cycling time trial

研究概览

简要总结

This research study revolves around the physiological outcomes of using post-exercise blood flow restriction (BFR) with high intensity short interval training (ST) The main aims of this study are to compare (i) aerobic performance outcomes, and (ii) anaerobic and muscular performance outcomes - between 2 groups of participants after either undergoing 3 weeks of ST + post-exercise BFR (BFR-ST) or traditional ST.

详细描述

This research study revolves around the physiological outcomes of using post-exercise blood flow restriction (BFR) with high-intensity interval exercise training (HIIT), specifically high intensity short interval training (ST) protocol of 30s work, 30s rest, for the recreational endurance athlete. In previous research, it has been shown that using BFR during rest intervals of a ST protocol would elicit greater physiological stresses in terms of higher heart rate, greater muscle activation, reduced oxygenation within the muscle tissue during exercise, and increased blood lactate post-exercise as compared with the control condition. However, the physiological outcomes of this type of training method over a longer-term (9 sessions over 3 weeks) have not been explored. The main aims of this study is to compare the physiological outcomes, - (i) aerobic performance outcomes, and (ii) anaerobic and muscular performance outcomes - between 2 groups of participants after either undergoing 3 weeks of ST + post-exercise BFR (BFR-ST) or traditional ST . The hypotheses for this study are: the BFR-ST group would experience a (i) greater improvement in maximal aerobic capacity, function and time trial performance and, (ii) greater improvement in anaerobic power and capacity as well as muscular strength and power, as compared with the ST group.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
Single (Participant)

盲法说明

Sham treatment of altitude exposure in an environmental chamber.

入排标准

年龄范围
18 Years 至 40 Years(Adult)
性别
Male
接受健康志愿者
是

入选标准

  • •18-40 years
  • •Actively performing endurance exercise (running or cycling) for at least 2 sessions (1 - 1.5h) per week
  • •Healthy (free from illnesses) and no musculoskeletal injuries for the past 6 months
  • •No history of cardiometabolic, vascular diseases or similar conditions (e.g., high blood pressure, peripheral vascular diseases, heart diseases, metabolic syndrome, diabetes, stroke, etc.).
  • •Pass the pre-participation health screening tests - Physical Activity Readiness Questionnaire for Everyone (PAR-Q+) and Australian Institute of Sport Blood Flow Restriction (AIS BFR) pre-screening questionnaire (no history of any risk factors).
  • •Achieve a maximum oxygen uptake (VO2max) of ≥40ml/kg/min during a maximal aerobic power cycling screening test.
  • •Non-smoker
  • •Drink alcohol less than 3 times each week and less than 3 drinks each time

排除标准

  • •Persons with any form of illnesses and/or musculoskeletal injuries for the past 6 months
  • •Any history of cardiometabolic, vascular diseases or similar conditions which may worsen with the use of blood flow restriction during exercise
  • •Fail the pre-participation health screening tests
  • •Below 40ml/kg/min VO2max during maximal aerobic power cycling test
  • •Consumption of alcohol beyond that stated in the inclusion criteria.
  • •History of asthma or taking medication for asthma.

研究组 & 干预措施

Blood flow restriction with short interval training (BFR-ST)

Experimental

9 sessions of high intensity short interval training with blood flow restriction.

干预措施: BFR-ST (Other)

Sham altitude with short interval training (ST)

Sham Comparator

9 sessions of high intensity short interval training in an altitude chamber.

干预措施: ST (Other)

结局指标

主要结局

20 km Cycling time trial

时间窗: Will be assessed at baseline (Day 0 - Pre) and the change in this outcome 24 hours after 9 sessions of training over 3 weeks (Post)

Maximum oxygen uptake and power

时间窗: Will be assessed at baseline (Day 0 - Pre) and the change in this outcome 24 hours after 9 sessions of training over 3 weeks (Post)

Wingate test of anaerobic power

时间窗: Will be assessed at baseline (Day 0 - Pre) and the change in this outcome 24 hours after 9 sessions of training over 3 weeks (Post)

Peak and mean power and rate of fatigue

次要结局

  • Exercise economy(Will be assessed at baseline (Day 0 - Pre) and the change in this outcome 24 hours after 9 sessions of training over 3 weeks (Post))
  • Isometric mid-thigh pull(Will be assessed at baseline (Day 0 - Pre) and the change in this outcome 24 hours after 9 sessions of training over 3 weeks (Post))
  • Countermovement jump height(Will be assessed at baseline (Day 0 - Pre) and the change in this outcome 24 hours after 9 sessions of training over 3 weeks (Post))

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Stephen Burns

Associate Professor

Nanyang Technological University

研究点 (1)

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