The effects of Grape Seed Extract in adolescents with Metabolic Syndrome
- Conditions
- Metabolic Syndrome.Hyperglycaemia, unspecified
- Registration Number
- IRCT2013112611288N7
- Lead Sponsor
- utrition Research Center,Tabriz University of Medical
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 44
Adolescents aged 13-19 years;waist circumference (WC) above the 90th percentile in adolescents under 16 years old and WC more than 95 centimeter in adolescents over 16 years old plus 2 or more of the following items; HDL<40 mg/dL ( In teenage girls over 16 years old:HDL<50 mg/dL ) ; TG = 150mg/dL; Fasting blood glucose = 100 mg/dL; Systolic blood pressure = 130 mmHg; Diastolic blood pressure = 85mmHg
Exclusion criteria: Suffering from heart disease ; Kidney disease ; Liver disease ; Hyperthyroidism or hypothyroidism; The use of anti-inflammatory drugs; smoking; Triglycerides above 500 mg per deciliter; Pregnancy in teenage girls
; The use of antioxidant supplements in the past three months; The use anticoagulant drugs , including aspirin , warfarin; Sensitivity to grapes
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method ipid profile (LDL, HDL, TG). Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Enzymatic methods and Friedewald formula.;Fasting Blood Glucose. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Measurement of fasting blood glucose by using kits.;HbA1c. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Using ion exchange chromatography.;Fasting Plasma Insulin. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Elisa.;Anthropometric Indices (weight , height, waist circumference , BMI). Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Using stadiometer, scale and tape.;Blood Pressure. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Mercury sphygmomanometer.
- Secondary Outcome Measures
Name Time Method Adiponectin. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Elisa kits.;Resistin. Timepoint: Before intervention and 8 weeks after intervention. Method of measurement: Elisa kits.