Periodontal Treatment Associated With Hyperbaric Oxygen Therapy
- Conditions
- Periodontal Disease
- Registration Number
- NCT00955643
- Lead Sponsor
- Escola Bahiana de Medicina e Saude Publica
- Brief Summary
Evaluation of the clinical effect of hyperbaric oxygen therapy (HBOT) adjunctively to scaling and root planing (SRP) in the treatment of severe case of chronic periodontitis.
- Detailed Description
Materials and Methods: In 20 patients diagnosed with severe generalized chronic periodontitis (pockets\>7mm) with bleeding on probing, SRP was rendered in all pockets. Additionally, five consecutive hyperbaric sessions were administered in 10 patients after random allocation (SRP+HBOT). Clinical parameters were assessed at baseline up to 6 months: plaque index (PI), bleeding on probing, probing depth, clinical attachment level and BANA test.
Results: SRP+HBOT resulted in greater probing reduction and attachment gain than SRP alone 3 months after treatment (p\<0.001). The BANA test was negative after 1 week only for sites in the SRP+HBOT group (p\<0.05). However SRP+HBOT failed to show a significant difference from SRP group after 3 months were all BANA sites became negative (p\>0.05).
Conclusion: These preliminary data suggest that hyperbaric oxygen therapy had a short-term beneficial effect on pocket reduction and bacterial elimination, and may be considered a potential therapy option to improve the clinical outcomes of scaling in severe cases of chronic periodontitis.
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 20
Not provided
Not provided
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
EBMSP Central Clinic
🇧🇷Salvador, Bahia, Brazil
EBMSP Central Clinic🇧🇷Salvador, Bahia, Brazil