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临床试验/CTRI/2025/04/083822
CTRI/2025/04/083822尚未招募不适用

Effect of Payasyadi Vasthi in Oligospermia

Dr Jithesh V1 个研究点 分布在 1 个国家目标入组 20 人开始时间: 2025年4月10日最近更新:

试验速览

阶段
不适用
状态
尚未招募
发起方
入组人数
20
试验地点
1
主要终点
a) Total sperm count

研究概览

简要总结

Infertility is defined as a failure to achieve a pregnancy after 12 months or more of regular unprotected coitus. Estimates suggest that approximately one in every six people of reproductive age worldwide experience infertility in their lifetime. According to recent report of WHO on status of infertility in India, of all infertility cases, approximately 50% is due to male factor infertility, owing to the reproductive anomalies in the male. Oligospermia is one of the major leading causes of male infertility. It is a condition of suboptimal concentration of spermatozoa in the ejaculated semen to ensure successful fertilization of an ovum. 2024 ICD

10 CM Code N46.1 define Oligospermia in human as a sperm count below 20 million per millilitre semen.

According to Ayurveda Oligospermia can be correlated to Ksheenasukra. Ksheenasukra is vata-pita predominant condition. Payasyadi vasthi is a vrishya vasthi having Brimhana and vata-pitta samana property. It is mentioned in Ashtanga hridayam kalpa sthanam and Charaka samhitha sidhisthana. Vasthi itself is a remedy for vata pradhana dosha. Hence the aim of the study is to find out the effect of Payasyadi Vasthi in Oligospermia.

The study design is Pre and post assessment interventional study with a sample size of 20 Males with an age group 25 to 50 years who are diagnosed with Oligospermia attending IPD of Govt. Ayurveda Panchakarma hospital, Thiruvananthapuram. Assessment of this study is done with quantitative semen analysis. Participants will be administered with Payasyadi Vasthi for continuous 7 days. The result will be assessed with regard to changes in the outcome variable as in semen analysis. The pre post test data will be assessed with appropriate statistical method.

Keywords: Oligospermia, Ksheena sukra, Payasyadi vasthi.

研究设计

研究类型
Interventional
分配方式
Na
盲法
None

入排标准

年龄范围
25.00 Year(s) 至 50.00 Year(s)(—)
性别
Male

入选标准

  • Participant of age group 25 to 50 years with total sperm concentration less than 20million per ml.
  • Participant fit for Enema as per Ayurvedic classical texts.

排除标准

  • Participant with Chronic uncontrolled Diabetes Mellitus, Hypertension.
  • Diagnosed case of Genetic defect like Klinefelter syndrome Bilateral Varicocele Accessory sex gland infections Diagnosed cases of STDs H/O lower lumbar spinal injury Any systemic disorder affecting testicular functions.

结局指标

主要结局

a) Total sperm count

时间窗: 0th day and 90th day

b) Sperm concentration

时间窗: 0th day and 90th day

次要结局

未报告次要终点

研究者

发起方
Dr Jithesh V
申办方类型
Other [self]
责任方
Principal Investigator
主要研究者

Dr Jithesh V

Government Ayurveda College Thiruvananthapuram

研究点 (1)

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