Clinical Efficacy and Safety of Lizhong Fuyuan Recipe Combined With Wenpi Powder Acupoint Application in the Treatment of Chronic Atrophic Gastritis With Spleen Deficiency and Phlegm Stasis

Phase 1

• Conditions: Chronic atrophic gastritis with spleen deficiency and phlegm stasis

• Registration Number: ITMCTR1900002704
• Lead Sponsor: Shanghai Traditional Chinese Medicine Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 20 February 2023

Recruitment & Eligibility

• Status: Pending
• Sex: All
• Target Recruitment: Not specified

Inclusion Criteria

1. The subjects were Asian patients aged 25 to 75 years of age with unlimited duration of disease and gender;
2. All of them were diagnosed as chronic atrophic gastritis by endoscopy before selection.
3. All of them were diagnosed as chronic atrophic gastritis by pathology before selection.
4. 5% of the patients were diagnosed as chronic atrophic gastritis by pathology. Patients who were diagnosed as HP negative by C13 breath test or gastroscopy, or were treated with HP (confirmed to be HP negative by C13 breath test or gastroscopy one month after the end of the course of treatment of western medicine combined with anti-HP);
5. 5% of the patients were confirmed to be negative by C13 breath test or gastroscopy after the end of the course of treatment of western medicine combined with anti-HP. Syndrome differentiation of traditional Chinese medicine is in accordance with the type of spleen deficiency and phlegm and blood stasis.
6. No other Chinese and Western medicine was used for a month.
7. Those who voluntarily participate in this clinical trial and sign informed consent.

Exclusion Criteria

1. Patients with gastric and duodenal ulcers;
2. Patients with upper gastrointestinal bleeding;
3. Gastric mucosa with high grade epithelial neoplastic or pathological diagnosis of suspected malignant transformation;
4. Patients with severe primary heart, liver, kidney, lung, blood system diseases, renal function Cr > normal reference value upper limit, liver function ALT >= normal reference value more than 1.5 times;
5. A patient who is pregnant or breast-feeding;
6. Those with skin diseases or skin allergies do not cooperate with the operator;
7. Mentally ill;
8. The researchers believe that patients who are not suitable for clinical trials, including patients with poor compliance, who cannot insist on medication for 6 months and who do not undergo gastroscopy after treatment, are not suitable for clinical trials.

Study & Design

• Study Type: Interventional study
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The pathological results of the gastric mucosa;