Effects of Structural exercise on Community dwelling older adults with Dementia
Trial Snapshot
- Phase
- Not Applicable
- Status
- Not Applicable
- Sponsor
- Enrollment
- 120
- Locations
- 1
- Primary Endpoint
- 1.Dementia Diagnosed by Mini-Mental State Examination (MMSE)
Study Overview
Brief Summary
This randomized controlled trial aims to evaluate the effects of a 12-week structured exercise program on physical and cognitive function in community-dwelling older adults with dementia. Participants will be randomly assigned to either an exercise group receiving strengthening, stretching, and mobility training, or a lifestyle modification group receiving health education and non-physical cognitive/social activities. Primary outcomes include balance, physical function, and daily living ability (MMSE, GDS, FRSSD, SF-36, and Likert Scale -sociodemographic). Secondary outcomes include Physical function (include handgrip test, TUG, BBS, and Chair-Stand Test at baseline, 3 and 6 months).
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Masking
- Participant and Outcome Assessor Blinded
Eligibility Criteria
- Ages
- 60.00 Year(s) to 95.00 Year(s) (—)
- Sex
- All
Inclusion Criteria
- •Community-dwelling older adults aged 60 years or above; MMSE score of 10 or more; clinically diagnosed dementia with dependence in at least one personal activity of daily living; able to stand up from a chair with armrests with help from one person or less; approved by physician; able to hear and understand instructions for assessments.
Exclusion Criteria
- •Participants will be excluded if they suffer from other neurological disease and severe diseases which would not allow participation in exercise (severe psychiatric illnesses, uncontrolled arterial hypertension, severe cardiorespiratory problems, severe musculoskeletal problems), cancer, surgery during the previous year, severe vision and/or hearing problems, or alcohol and/or drug abuse.
Outcomes
Primary Outcomes
1.Dementia Diagnosed by Mini-Mental State Examination (MMSE)
Time Frame: Baseline at 3 months, 6 months
2. Depression by Geriatric Depression Scale (GDS)
Time Frame: Baseline at 3 months, 6 months
3.Daily living functionality by Functional Rating Scale for Symptoms of Dementia (FRSSD).
Time Frame: Baseline at 3 months, 6 months
4.Quality of life by SF-36 short edition.
Time Frame: Baseline at 3 months, 6 months
5.Likert Scale for sociodemographic question
Time Frame: Baseline at 3 months, 6 months
Secondary Outcomes
- 1. Physical function assessed by using handgrip test, Timed Up to Go (TUG), Berg Balance Scale (BBS) and Chair-Stand Test (CST)(Baseline at 3 months, 6 months)
Investigators
Al Amin
Jashore University of Science and Technology