Estimation of protein levels in the saliva before and after scaling and root planing procedure
Phase 1
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2020/04/024689
- Lead Sponsor
- Rinu Reju
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Inclusion Criteria
Generalized Gingivitis Patient:
Individual with at least 20 remaining teeth with:
Gingival index > 20%
Bleeding on probing > 20% of sites
Probing depth <= 4mm
Clinical attachment loss <1mm
Generalized Chronic Periodontitis Patient
Individual with at least 20 remaining teeth with:
Gingival Index >20%
Bleeding on Probing > 20%
Probing Depth > 4mm
Clinical Attachment Loss >= 1mm
Exclusion Criteria
Any periodontal surgery in the past 6 months.
Any chronic diseases, infectious diseases, immunological diseases, pregnancy, lactation, smoking (current or former smoker for 10 years).
Use of medications such as: antibiotics, anti-inflammatory drugs, steroids, immunosuppressants, anticoagulants, and lipid-lowering drugs.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To assess the effectiveness of salivary myeloperoxidase as a marker of periodontal disaeseTimepoint: 1 month and 3 months
- Secondary Outcome Measures
Name Time Method All the clinical parameters along with the MPO level will be assessed at baseline in Gingivitis and Chronic Periodontitis patients. Then after non-surgical periodontal therapy these parameters along with the MPO levels will be assessed again after 1 month and after 3 monthsTimepoint: 1 month and 3 months