Saliva characteristics in health and disease
- Conditions
- Health Condition 1: null- (22 oral cancer, 22 potentially malignant lesions, 22 tobacco usersand 22 controls)
- Registration Number
- CTRI/2018/01/011566
- Lead Sponsor
- Manipal College of Dental Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- ot Yet Recruiting
- Sex
- Not specified
- Target Recruitment
- 0
Oral cancer group: Histopathologically confirmed cases of Oral cancer and who were above 18 years of age would be included.
Potentially malignant lesions group: Histopathologically confirmed cases of potentially malignant lesions (leukoplakia, oral sub-mucous fibrosis) and who were above 18 years of age would be included.
Tobacco users group: Known habitual tobacco users (of more than 1 year smoking or smokeless tobacco) and who were above 18 years of age would be included.
Control groups: Healthy individuals, without the habit of tobacco, with no gross pathologies and
who were above 18 years of age would be included.
Patients with systemic disease, patient had a history of prior
malignancy, immunodeficiency, other autoimmune disorders, hepatitis, or human
immunodeficiency virus infection; and prior treatment in the form of chemotherapy,
radiotherapy, surgery or alternative medicine, pregnancy or lactation
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Salivary MMP - 9Timepoint: Baseline (immediately)
- Secondary Outcome Measures
Name Time Method ATimepoint: NA