Evaluation of Salivary Matrixmetalloproteinase-8 levels when ozonated olive oil gel is used as an adjunct to non surgical periodontal therapy
Not Applicable
Completed
- Conditions
- Health Condition 1: K053- Chronic periodontitis
- Registration Number
- CTRI/2022/06/042993
- Lead Sponsor
- Samhitha Kothapalli
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 40
Inclusion Criteria
1. Age group 25-55 years.
2. Subjects who are apparently healthy.
3. Probing pocket depth and clinical attachment level of =5mm.
4. Radiographic evidence of horizontal bone loss.
5. Patients who gave informed consent for the study.
Exclusion Criteria
1. Radiographic evidence of vertical boneloss
2. Patients who has history of drug allergy.
3. Any form of tobacco consumption.
4. Pregnancy or lactating females.
5. History of any form of periodontal therapy in the past 1 year.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method To evaluate salivary MMP-8 and periodontal parameters at baseline and 3 months after NSPT with ozonated olive oil gel application. <br/ ><br>2. To evaluate salivary MMP-8 levels and periodontal parameters at baseline and 3 months after NSPT with placebo gel application. <br/ ><br>Timepoint: baseline and 3 months
- Secondary Outcome Measures
Name Time Method To evaluate salivary MMP-8 and periodontal parameters at baseline and 3 months after NSPT with ozonated olive oil gel application. <br/ ><br>2. To evaluate salivary MMP-8 levels and periodontal parameters at baseline and 3 months after NSPT with placebo gel application. <br/ ><br>Timepoint: baseline and 3 months