MedPath

Single Versus Double Hamstring Harvest for Anterior Cruciate Ligament Reconstruction

Not Applicable
Conditions
Anterior Cruciate Ligament Injury
Interventions
Procedure: single-bundle, single-hamstring ACL reconstruction
Procedure: single-bundle, double-hamstring ACL reconstruction
Registration Number
NCT03626883
Lead Sponsor
Rafał Kamiński
Brief Summary

The aim of the study is to examine the influence of number of the harvested hamstring tendons on subjective and objective outcomes of primary anterior cruciate ligament reconstruction.

Detailed Description

The aim of the study is to examine the influence of number of the harvested hamstring tendons on subjective (patient-reported outcome measures) and objective (instrument-tested and imaging studies) outcomes of primary anterior cruciate ligament reconstruction.

The study will recruit 60 patients per each of two arms.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
120
Inclusion Criteria
  • chronic anterior knee instability with MRI-confirmed anterior cruciate ligament tear
Exclusion Criteria
  • revision anterior cruciate ligament surgery
  • other lower limb injuries

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
1 hamstringsingle-bundle, single-hamstring ACL reconstructionPatients will receive the intervention of 'single-bundle, single-hamstring ACL reconstruction'.
2 hamstringssingle-bundle, double-hamstring ACL reconstructionPatients will receive the intervention of 'single-bundle, double-hamstring ACL reconstruction'.
Primary Outcome Measures
NameTimeMethod
Knee stability (KT1000 assessment), pivot shift at 2,4 and 5yrs time-pointsup to 5yrs
Secondary Outcome Measures
NameTimeMethod
Change from baseline Lysholm Knee Questionnaire at 104 weeksup to 5yrs

Knee function questionnaire (patient-administered), minimum score: 0, maximum score: 100. Full description in: Lysholm J, Gillquist J. Evaluation of knee ligament surgery results with special emphasis on use of a scoring scale. Am J Sports Med. 1982; 10:150-4. \[PubMed: 6896798\]

Need for arthrocentesis, revision surgery, additional procedures up to 104 weeksup to 5yrs

The medical records will be prospectively abstracted and analyzed for any arthrocentesis, revision surgery or additional procedures performed in the study group up top 104 weeks after index surgery.

Change from baseline tunnel volume at 104 weeks104-weeks postop

Change from baseline tunnel volume will be calculated on magnetic resonance imaging images at 104 weeks postoperatively

Change from baseline International Knee Documentation Committee (IKDC) Subjective Knee Evaluation Form at 104 weeksup to 5yrs

Anderson, AF. Rating scales. In: Fu, FH.; Harner, CD.; Vince, KL., editors. Knee surgery.

Baltimore: Williams \& Wilkins; 1994. p. 275-96.

Change from baseline Knee injury and Osteoarthritis Outcome Score at up to 5yrsup to 5yrs

Knee injury and Osteoarthritis Outcome Score minimum score:0, maximum score:100 Baltimore: Williams \& Wilkins; 1994. p. 275-96.

Change from baseline Visual Analog Scale for Pain at 104 weeksup to 5yrs

Separate Outcome Measure, with minimum 0 and maximum of 10. Full description in: Hawker GA, Mian S, Kendzerska T, French M. Measures of adult pain: Visual Analog Scale for Pain (VAS Pain), Numeric Rating Scale for Pain (NRS Pain), McGill Pain Questionnaire (MPQ), Short-Form McGill Pain Questionnaire (SF-MPQ), Chronic Pain Grade Scale (CPGS), Short Form-36 Bodily Pain Scale (SF-36 BPS), and Measure of Intermittent and Constant Osteoarthritis Pain (ICOAP).

Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11:S240-52. doi:10.1002/acr.20543.

Change from baseline tunnel diameter at 104 weeks104-weeks postop

Change from baseline tunnel diameter will be calculated on standing knee x-rays at 104 weeks postoperatively

Trial Locations

Locations (1)

Prof. A. Gruca Teaching Hospital, Centre for Postgraduate Medical Education

🇵🇱

Otwock, Woj. Mazowieckie, Poland

© Copyright 2025. All Rights Reserved by MedPath