Intensity Modulated Radiation Therapy (IMRT) Radiotherapy for Treating Prostate Pelvic Nodes
- Conditions
- Prostate Cancer
- Registration Number
- NCT00214136
- Lead Sponsor
- University of Wisconsin, Madison
- Brief Summary
The purpose of this study is to examine the clinical feasibility and efficacy of uing IMRT to escalate the biologically effective dose to the pelvic lymph nodes in a short course of radiation therapy. An increased total and biologically effective dose will be delivered to the pelvic lymph nodes (56 Gy at 2 Gy/fraction). The prostate will receive standard "short course" IMRT of radiation (70 Gy at 2.5 Gy/fraction).
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- Male
- Target Recruitment
- 30
- Prostate cancer stage T-T3
- Predicted risk of lymph node involvement > 15%
- Gleason > 7
- Distance metastases
- Use of anti-coagulant therapy
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- SINGLE_GROUP
- Primary Outcome Measures
Name Time Method Number of Participants Experiencing Expected Toxicities Up to 5 years Tolerances to high dose RT to Pelvic Lymph nodes in treatment of prostate cancer; measured by participants experiencing expected toxicities.
- Secondary Outcome Measures
Name Time Method To Evaluate Local Tumor Control and Biochemical Progression-free and Metastasis-free Survival 5 years Clinically evaluate local tumor control and biochemical progression-free and metastasis-free survivals.
Trial Locations
- Locations (1)
University Of Wisconsin Hospital and Clinics
🇺🇸Madison, Wisconsin, United States
University Of Wisconsin Hospital and Clinics🇺🇸Madison, Wisconsin, United States