MedPath

Phase 2 Study of VELCADE Alone or VELCADE® Plus Docetaxel in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer

Phase 2
Completed
Conditions
Non-Small Cell Lung Cancer
Registration Number
NCT00051974
Lead Sponsor
Millennium Pharmaceuticals, Inc.
Brief Summary

The purpose of this study is to evaluate how tumors in patients with non-small cell lung cancer respond to treatment with VELCADE alone versus VELCADE given with docetaxel and also to see what effects (good and bad) it has on you and your cancer.

Detailed Description

In this study, patients with non-small cell lung cancer that is no longer responding to standard medical treatment with another anti-cancer drug will be randomly chosen to receive treatment with VELCADE alone or VELCADE in combination with docetaxel. Patients have almost equal chance of getting into either of the two treatment arms listed above.

Recruitment & Eligibility

Status
COMPLETED
Sex
All
Target Recruitment
155
Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod

Trial Locations

Locations (20)

Cedars-Sinai Comprehensive Cancer Center

🇺🇸

Los Angeles, California, United States

UCLA Medical Center Thoracic Malignancy

🇺🇸

Los Angeles, California, United States

Atlanta VAMC

🇺🇸

Decatur, Georgia, United States

Washington University, Barnard Cancer Center

🇺🇸

St. Louis, Missouri, United States

Univeristy of Florida Shands Cancer Center

🇺🇸

Gainesville, Florida, United States

St. Louis University Health Sciences Center

🇺🇸

St. Louis, Missouri, United States

University of Wisconsin Comprehensive Cancer Center

🇺🇸

Madison, Wisconsin, United States

Vanderbilt University-Clinical Trials Center

🇺🇸

Nashville, Tennessee, United States

University of Colorado Health Sciences Center

🇺🇸

Aurora, Colorado, United States

University of Texas MD Anderson Cancer Center

🇺🇸

Houston, Texas, United States

Hunstman Cancer Institute-University of Utah

🇺🇸

Salt Lake City, Utah, United States

Mass. General Hospital Hem/Onc. Associates

🇺🇸

Boston, Massachusetts, United States

Duke University Medical Center

🇺🇸

Durham, North Carolina, United States

U of Alambama at Birmingham Comprehensive Cancer Center

🇺🇸

Birmingham, Alabama, United States

Sylvester Comprehensive Cancer Center

🇺🇸

Miami, Florida, United States

Winship Cancer Institute

🇺🇸

Atlanta, Georgia, United States

DBA Kansas City Cancer Centers

🇺🇸

Kansas City, Missouri, United States

Carolinas Hematology-Oncology Associates

🇺🇸

Charlotte, North Carolina, United States

Kimmel Cancer Center at Jefferson

🇺🇸

Philadelphia, Pennsylvania, United States

Yale University School Of Medicine

🇺🇸

New Haven, Connecticut, United States

© Copyright 2025. All Rights Reserved by MedPath