Action Prediction in Autism Spectrum Disorders
Completed
- Conditions
- Autism10012562Autism Spectrum Disorder
- Registration Number
- NL-OMON40834
- Lead Sponsor
- Radboud Universiteit Nijmegen
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- Not specified
- Target Recruitment
- 66
Inclusion Criteria
- right-handed, between 12 and 18 years old, IQ higher than 80
- Autism group: clinical diagnosis of autism spectrum disorder
Exclusion Criteria
- psychiatric (co-)morbidity, history of epilepsy, visual impairments
Study & Design
- Study Type
- Observational non invasive
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method <p>Based on previous findings, we expect that healthy controls predict the<br /><br>different action steps of the presented action sequences and that their<br /><br>predictions become faster for the later action steps, reflecting the<br /><br>integration of the contextual information. For the ASD group on the other hand,<br /><br>we expect to see less predictions and no improvement for the last action steps,<br /><br>reflecting a prediction difficulty and a deficit in integration of information<br /><br>as suggested by previous literature. In addition, we expect to find group<br /><br>differences in neural connectivity, measured by means of EEG coherence<br /><br>analysis. In addition, we aim to explore changes in EEG coherence related to<br /><br>action prediction and finally assess group differences.</p><br>
- Secondary Outcome Measures
Name Time Method <p>Behavioural task performance during the EEG-ET task will be used assess the<br /><br>compliance of the participants and ensure both groups were equally able to<br /><br>perform the task. Age, AQ, IQ, and gender will be taken into consideration as<br /><br>covariates in the statistical tests.</p><br>