Effect of optical quality on retinal thresholds

Completed

• Conditions: Glaucoma; POAG; 10018307

• Registration Number: NL-OMON46489
• Lead Sponsor: niversitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 15 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 50

Inclusion Criteria

Phakic and pseudophakic POAG and PACG patients and phakic PAC patients scheduled for CLE, who visit the ophthalmology clinic at University Medical Center Groningen, that have provided the signed informed consent form and meet the inclusion-exclusion criteria. Healthy subjects between ages 50 and 75, who have provided the signed informed consent form and returned the questionnaire with results which do not indicate ophthalmic abnormalities.

Exclusion Criteria

POAG patients;Visual acuity less than 0.8
Refractive surgery (LASIK, LASEK, RK, PRK, etc.)
Non-glaucomatous visual field loss
History of closed or blocked angle
Myopia or hyperopia higher than 3D
For pseudophakic patients only: IOL model implanted different than TECNIS Monofocal, Model ZCB00 (default lens in UMCG) and preoperative myopia/hyperopia higher than 3D

Phakic PAC patients scheduled for CLE;Visual acuity less than 0.8
Refractive surgery (LASIK, LASEK, RK, PRK, etc.)
Non-glaucomatous visual field loss
IOL model to be implanted different than TECNIS Monofocal, Model ZCB00 and preoperative myopia higher than 3D;Healthy Subjects;Visual acuity less than 0.8
Refractive surgery (LASIK, LASEK, RK, PRK, contact lenses, etc.)
Any visual field loss
Intraocular pressure above 21 mmHg
Positive family history of glaucoma
Myopia/hyperopia higher than 3D
Angle closure more than 180 degrees
For pseudophakic patients only, IOL model implanted different than TECNIS Monofocal, Model ZCB00 and preoperative myopia/hyperopia higher than 3D

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Optical aberrations measured using aberrometry and retinal sensitivity<br /><br>thresholds measured by means of perimetry. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Corneal aberrations, ocular biometry, ocular scatter, intraocular pressure,<br /><br>visual acuity and refraction these parameters are used for descriptive<br /><br>statistics, to characterize the study population.</p><br>