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Comparison of visual acuity and macular thickness in patients with macular edema cuased by branch retinal vein occlusion treated with intravitral avastin and intravitral avastin and tissue plasminogen activator

Not Applicable
Conditions
Retinal vein occlusion.
Retinal vein occlusion_ partial
Registration Number
IRCT2014072618596N1
Lead Sponsor
Vice chancellor for Research and Technology, Tabriz University of Medical Science
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
Complete
Sex
All
Target Recruitment
50
Inclusion Criteria

1) Having the diagnosis of BRVO. 2) Slit lamp examination: macular edema. 3) Snellen visual acuity: vision worse than 20/40. 4) Optical coherence tomography finding: central macular thickness of 250µm and over on.

Exclusion: 1) BRVO associated with vitrous hemorrhage. 2) previous treatment with laser photocoagulation. 3) History of previous vitrectomy. 4)Intraocular pressure more than 21 mmhg. 5) Uncontrolled diabetes. 6) Systemic blood pressure. 7) Uveitis. 8) Any evidence of posterior vitrous detachment.

Exclusion Criteria

Not provided

Study & Design

Study Type
interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Visual acuity. Timepoint: Before intervention, one month, 3 months, 6 months after intervention. Method of measurement: Snellen chart.;Central macular thickness. Timepoint: Before intervention, one month, 3 months, 6 months after intervention. Method of measurement: Optical Coherence tomography.
Secondary Outcome Measures
NameTimeMethod
Endophthalmitis. Timepoint: 1, 3 and 6 month after intervention. Method of measurement: clinical.
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