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临床试验/NCT01890616
NCT01890616已完成不适用

Constipation and Gut Transit in Duchenne Muscular Dystrophy Patients

Children's Hospital Medical Center, Cincinnati1 个研究点 分布在 1 个国家目标入组 8 人开始时间: 2013年5月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
8
试验地点
1
主要终点
GI transit times

研究概览

简要总结

In this research study the investigators want to screen Duchenne Muscular Dystrophy (DMD) patients for signs and symptoms of constipation in patients over 18.

The investigators hypothesized:

  • DMD patients have a high prevalence of constipation than in the general population.
  • Prevalence of constipation will increase with age and with worsening functional status.

详细描述

The following procedures will take place during the study.

Constipation Assessment:

  • The patient will be asked to complete a questionnaire about any symptoms of constipation.
  • A physician from the study team will perform an abdominal physical exam
  • The patient will have routine x-rays that monitor for spine compression fractures. These films will also be used to assess stool content.

Clinical Information The following information will also be collected during the clinic visit ;

  • Age at diagnosis and genetic mutation
  • Age at loss of ambulation if applicable
  • Medications
  • Functional status

研究设计

研究类型
Observational
观察模型
Case Only
时间视角
Prospective

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Male
接受健康志愿者

入选标准

  • Patients with a diagnosis of Duchenne Muscular Dystrophy (based on clinical presentation and verified by compatible muscle biopsy or known dystrophin gene mutation).
  • Age greater than or equal to 18 years old

排除标准

  • 未提供

结局指标

主要结局

GI transit times

时间窗: up to 5 days

Gi transit times will be computed by an investigator.

次要结局

未报告次要终点

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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