Evaluation of Efficacy of Ultrasound Guided Transversus Abdominis Plane Block in Multimodal Regimen for Postoperative Analgesia after Total Abdominal Hysterectomy done under Combined Spinal Epidural Anaesthesia.

This study is a randomized, double blind, parallel group, evaluating efficacy of  Ultrasound guided Transversus Abdominis Plane (TAP) block in multimodal regimen after total abdominal hysterectomy patients done under combined spinal epidural aneasthesia technique in India. Subjects randomized in to two groups, Control group will receive standard postoperative analgesic treatment while study group will receive standard postoperative analgesic treatment and TAP block. The primary outcome measure will be assessment of duration of analgesia postoperatively within 24 hours. Secondary outcomes will be epidural morphine consumption, pain severity using visual analogue scores, Incidence of nausea-vomiting, pruritus, sedation and respiratory depression, complication of TAP block, Adverse effect of drug and patient satisfaction at 0, 2, 4, 6, 8, 10, 12, 18 and 24 hours.