Role of abdominal block for postoperative pain relief after total abdominal hysterectomy.

Not yet recruiting

• Conditions: Postoperative pain

• Registration Number: CTRI/2018/01/011163
• Lead Sponsor: Tata Motors Hospital

Brief Summary

This study is a randomized, double blind, parallel group, evaluating efficacy of  Ultrasound guided Transversus Abdominis Plane (TAP) block in multimodal regimen after total abdominal hysterectomy patients done under combined spinal epidural aneasthesia technique in India. Subjects randomized in to two groups, Control group will receive standard postoperative analgesic treatment while study group will receive standard postoperative analgesic treatment and TAP block. The primary outcome measure will be assessment of duration of analgesia postoperatively within 24 hours. Secondary outcomes will be epidural morphine consumption, pain severity using visual analogue scores, Incidence of nausea-vomiting, pruritus, sedation and respiratory depression, complication of TAP block, Adverse effect of drug and patient satisfaction at 0, 2, 4, 6, 8, 10, 12, 18 and 24 hours.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-01-15
• Last Update Posted: 2018-04-01

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: Female
• Target Recruitment: 74

Inclusion Criteria

• All patients undergoing total abdominal hysterectomy under combined spinal epidural anaesthesia after obtaining informed consent.
• ASA grade I-III.
• Total abdominal hysterectomy performed via lower abdominal transverse (Pfannenstiel) incision.

Exclusion Criteria

• Patient refusal.
• A history of drug allergy or local anaesthetic toxicity.
• BMI >35kg/m2 (to limit maximum Ropivacaine dose to 3mg/kg) Contraindications to regional anaesthesia (bleeding diathesis, infection at the site of block and peripheral neuropathy) Change of anaesthetic technique to general anaesthesia.
• Failure or complication in epidural catheter insertion.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Duration of analgesia	0,2,4,6,8,10,12,18 and 24 hr.

Secondary Outcome Measures

Name	Time	Method
Epidural morphine consumption.	Severity of pain.

Trial Locations

Locations (1)

Tata Motors Hospital; 🇮🇳 Singhbhum, JHARKHAND, India

Tata Motors Hospital

🇮🇳Singhbhum, JHARKHAND, India

Motaka Mayurkumar

Principal investigator

8092612434

mayur71039@gmail.com