NL-OMON40004
Completed
Not Applicable
The role of β-adrenergic stress hormones in Eye Movement Desensitization and Reprocessing (EMDR). Part I: the effects of β-adrenergic receptor antagonist propranolol on the plasticity of emotionally arousing episodic memories. - The role of β-adrenergic stress hormones in EMDR: a propranolol study
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Geen aandoening: geneesmiddel wordt gebruikt om de onderliggende neurobiologische processen te onderzoeken van een therapie voor PTSD, namelijk EMDR
- Sponsor
- niversiteit Utrecht
- Enrollment
- 60
- Status
- Completed
- Last Updated
- last year
Overview
Brief Summary
No summary available.
Investigators
Eligibility Criteria
Inclusion Criteria
- •\- Passing the medical screening (ECG, blood pressure and heart rate examination, two\-step test and interview)
- •\- Age 18\-35
- •\- BMI 17\.5\-26
- •\- Normal (or corrected to normal) vision
- •\- In females: the use of reliable contraceptives (birth control pills or a hormonal intrauterine device)
Exclusion Criteria
- •Assessed with physical exam:
- •\- Abnormal ECG
- •\- Systolic blood pressure \< 60mmHg; Diastolic blood pressure \< 90 mmHg
- •\- Heart rate \< 60 bpm or \> 100 bpm
- •\- No \<10% increase in heart rate after 1 minute of stepping up and down a stepladder.;Assesed with interview:
- •\- Familiarity with EMDR and/or prior participation in EMDR research
- •\- Lifetime history of psychiatric disorder (depression, mania, psychosis, anxiety)
- •\- Lifetime history of neurological disease (attention/memory problems and disorders, epilepsy, convulsions)
- •\- Lifetime history of any cardiovascular problem, coronary insufficiency, congestive heart failure, heart block, bradycardia, myocardial infarction, hypotension, chronic obstructive pulmonary disease, bronchial asthma, renal disorders, liver disorders, uraemia, hyperthyroidism, acidosis.
- •\- Early age cardiovascular problems in first degree family members
Outcomes
Primary Outcomes
Not specified
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