NL-OMON40004已完成不适用
The role of β-adrenergic stress hormones in Eye Movement Desensitization and Reprocessing (EMDR). Part I: the effects of β-adrenergic receptor antagonist propranolol on the plasticity of emotionally arousing episodic memories. - The role of β-adrenergic stress hormones in EMDR: a propranolol study
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 60
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- 18 至 99(—)
入选标准
- •- Passing the medical screening (ECG, blood pressure and heart rate examination, two-step test and interview)
- •- Age 18-35
- •- BMI 17.5-26
- •- Normal (or corrected to normal) vision
- •- In females: the use of reliable contraceptives (birth control pills or a hormonal intrauterine device)
排除标准
- •Assessed with physical exam:
- •- Abnormal ECG
- •- Systolic blood pressure < 60mmHg; Diastolic blood pressure < 90 mmHg
- •- Heart rate < 60 bpm or > 100 bpm
- •- No <10% increase in heart rate after 1 minute of stepping up and down a stepladder.;Assesed with interview:
- •- Familiarity with EMDR and/or prior participation in EMDR research
- •- Lifetime history of psychiatric disorder (depression, mania, psychosis, anxiety)
- •- Lifetime history of neurological disease (attention/memory problems and disorders, epilepsy, convulsions)
- •- Lifetime history of any cardiovascular problem, coronary insufficiency, congestive heart failure, heart block, bradycardia, myocardial infarction, hypotension, chronic obstructive pulmonary disease, bronchial asthma, renal disorders, liver disorders, uraemia, hyperthyroidism, acidosis.
- •- Early age cardiovascular problems in first degree family members
- •- Fainting easily (can be indicative of cardiovascular problems).
- •- Inability to adequately read or speak Dutch
- •- Use of any contraindicative medication:
- •- Medication that decreases blood pressure, or cardiac contractility or conductivity
- •- Medication for migraine, dizziness, asthma, tuberculosis, psoriasis
- •- Medication that lowers blood sugar levels
- •- Anti-inflammatory painkillers
- •- Anti-depressives
- •- Anti-psychotics
- •- Anxiolytics
- •- Antacids
- •- Recreational drug use other than alcohol in the past 3 months
- •- Known sensitivity to propranolol
- •- Daily smoking (>=10 cigarettes per day)
- •- Excessive drinking (>=4 glasses per day)
研究者
相似试验
尚未招募
不适用
The effects of yohimbine on episodic memory retrieval and reconsolidation during EMDRYohimbine, Emotional memory, EMDR, Eye movements, Noradrenalin, β-adrenergic stress hormonesNL-OMON26672trecht University60
尚未招募
不适用
The role of adrenal stress hormones in emotional memory: formation, consolidation, and reconsolidatiostress related mental disorders10002861NL-OMON30998niversitair Medisch Centrum Sint Radboud160
尚未招募
2 期
Physiology of brown fat in humansObesityACTRN12611001198910HMRC70
招募中
Unknown
The Effect of Stress on Neuroendocrine Markers and Functional Connectivity in Children and Adolescents with Depressive and Anxiety DisordersF32.1F32.2F32.3F33.1F33.2F33.3F40.0F40.00F40.01F40.1F41.0Moderate depressive episodeSevere depressive episode without psychotic symptomsSevere depressive episode with psychotic symptomsRecurrent depressive disorder, current episode moderateRecurrent depressive disorder, current episode severe without psychotic symptomsRecurrent depressive disorder, current episode severe with psychotic symptomsSocial phobiasPanic disorder [episodic paroxysmal anxiety]AgoraphobiaDRKS00032507Klinik und Poliklinik für Kinder- und Jugendpsychiatrie der Universität Regensburg am Bezirksklinikum Regensburg90
尚未招募
不适用
Role of beta-blocker in Stroke outcome.CTRI/2022/07/043879Prinicipal Investigator
