Induction of Donor-Specific Tolerance in Renal Allograft Recipients (Living Donor) With TAIZ-Monocytes

Phase 1

• Conditions: Renal Transplantation

• Registration Number: NCT00223067
• Lead Sponsor: University Hospital Schleswig-Holstein

Brief Summary

reduce of immunsupression or introduce tolerance with so called TAIZ-monocytes in renal transplant patients

Detailed Description

Not available

Study Timeline

• Status Verified: 2004-04
• Study Start: 2005-03
• Study First Submitted: 2005-09-14
• Study First Submitted QC: 2005-09-14
• Study First Posted: 2005-09-22
• Last Update Submitted: 2005-10-27
• Last Update Posted: 2005-10-28
• Study Completion: 2006-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

Not provided

Exclusion Criteria

Not provided

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Primary Outcome Measures

Name	Time	Method
graft survival and reduction or withdrawal of immunosuppressives after treatment with Transplant-Acceptance Inducing Cells (TAIC) and autologous regulatory T cells (tregs)
serum creatinine
rejection episodes
necessity for re-introduction of any immunosuppressives.

Secondary Outcome Measures

Name	Time	Method
safety and tolerability of the treatment with Transplant-Acceptance Inducing Cells (TAIC) in terms of rejection episodes and Adverse Events (AEs)

Trial Locations

Locations (1)

University of Schleswig-Holstein, Campus Kiel, Department of Nephrology; 🇩🇪 Kiel, Germany