Effects of Whey Protein and Collagen Supplementation on Muscle Mass and Function During Training in Young Adults
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 22
- 试验地点
- 2
- 主要终点
- Change in mean power
研究概览
简要总结
The present project aims to investigate the effects of high-quality protein (whey protein) vs. low-quality protein (collagen) on muscle mass and function (e.g., strength and power) during a 10-wk resistance training program in young adults. It will be tested the hypothesis that leucine-matched collagen should promote similar gains on muscle function and mass compared to whey protein supplementation.
详细描述
The purpose of this study will be to investigate the effects of whey protein vs. leucine-matched collagen supplementation on muscle mass and function after a 10-wk resistance training program. Initially, all participants will be submitted for a 2-wk familiarization period, and then randomized into two groups (N = 11 / group): whey protein group and leucine-matched collagen group. The following variables will be assessed from pre-to post-training: anthropometric, muscle thickness from vastus lateralis and biceps brachii muscles using ultrasound, training load, mean power and peak torque for unilateral arm flexion exercise using a isokinetic dynamometer, countermovement vertical jump, nutritional intake, and testosterone-to-cortisol ratio . Shapiro-Wilk and Levine tests will be used to test the normality and homogeneity of the measurements, respectively. Two-way ANOVA (group x time) tests for repeated measures will be performed to assess changes over time and between groups for all dependent variables. Violation of sphericity will adjust using Greenhouse- Geyser correction. The Bonferroni post-hoc test will detect specific differences between groups. When appropriate, the percentage of change (∆%) will be reported according to the following equation: ∆% = [(pre-average post average) / pre-average mean] × 100. Values will be express as mean ± standard deviation. O significance level α will be 0.05.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- Double (Participant, Investigator)
入排标准
- 年龄范围
- 18 Years 至 35 Years(Adult)
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Men and women aged 18-35 years
- •To be eutrophic (not overweight or obese)
排除标准
- •To present a history of musculoskeletal disorders
- •Be attending a systematized weight training program for at least six months
- •To make use of medicines that could affect muscle function.
- •To have used ergogenic supplements and anabolic steroids for at least six months before study
- •To have restrictions for exercises practice considering Physical Activity Readiness Questionnaire (PAR-Q) responses.
结局指标
主要结局
Change in mean power
时间窗: Baseline and after 10 weeks
Mean power using a isokinetic dynamometer (BIODEX)
Change in peak torque
时间窗: Baseline and after 10 weeks
Peak torque using a isokinetic dynamometer (BIODEX)
Change in biceps brachii thickness
时间窗: Baseline and after 10 weeks
Measured by ultrasonography pre- and post-training
Change in vastus lateralis thickness
时间窗: Baseline and after 10 weeks
Measured by ultrasonography pre- and post-training
Change in vertical jump
时间窗: Baseline and after 10 weeks
Countermovement vertical jump performance will be assessed using the Smart Jump instrument
Change in muscle strength by training load
时间窗: Baseline, 5 and 10 weeks
Training load for leg press, knee extension, and arm flexion exercises
次要结局
- Change in testosterone-to-cortisol ratio(Baseline and after 10 weeks)
- Dietary intake(Baseline, 2, 5, 10 weeks)
研究者
Andreo Fernando Aguiar
Principal Investigator
Universidade Norte do Paraná
