The expression of AQP5 and UTs in the sweat glands of uremic patients
Phase 1
- Conditions
- 11 patients with normal renal function who underwent abdominal surgery and were excluded from chronic disease were recruitedas control groups.
- Registration Number
- TCTR20170810005
- Lead Sponsor
- Jing Lv
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Enrolling by invitation
- Sex
- All
- Target Recruitment
- 45
Inclusion Criteria
1. Laboratory diagnosised end-stage renal disease. 2. undergoing catherization for peritoneal dialysis.
Exclusion Criteria
patients with chronic diseases such as chronic hepatitis, skin disease and systemic lupus erythematosus were excluded.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The abundance of UT-A1 and UT-B1 in uremic sweat glands is significantly increased in uremic patient 01/12/2016 Immunohistochemistry, immunofluorescence, RT-PCR and Western Blot
- Secondary Outcome Measures
Name Time Method The expression of AQP5 is significantly decreased in uremic patients. 01/12/2016 Immunohistochemistry, immunofluorescence, RT-PCR and Western Blot