The Clinical Profile of Parkinson Disease in Egypt: A Retrospective Cohort Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,237
- 主要终点
- time to L-Dopa start
研究概览
简要总结
Multi-center, retrospective observational cohort study in 4 tertiary referral centers in Cairo over the period from 2004 to 2016.
Study population. including all patients with idiopathic Parkinson disease attending. Patients were diagnosed in accordance to the United Kingdom - Parkinson Disease Society Brain Bank criteria.
详细描述
Retrospective, observational study that involve Medical Record Review (MRR). Data extraction and collection from medical records was organized through an electronic structured data collection form by two of authors (H.S and N.S).
The abstraction documents included; patient's age, sex, family history, age at onset, type and side of motor symptoms onset, associated non-motor manifestations. Moreover; management plan, drug history, outcome and disease progression were also verified and recorded.
During medical record reviewing (MRR); any missing documentation or poorly recorded information was managed by deleting the case.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 25 Years 至 85 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All patients with Parkinsonian syndromes
排除标准
- •Records with missing operationalized variables from patient records
结局指标
主要结局
time to L-Dopa start
时间窗: 6 - 12 months
The time to L-Dopa start from symptoms onset in relation to time of Diagnosis
次要结局
未报告次要终点
研究者
Hatem Samir Shehata
Professor
Cairo University