TaNeMo Study: The physiological effects of repetitive neuromuscular magnetic stimulation (rNMS) as a basis for therapy target-adapted neuromodulation [study period A]
Not Applicable
Recruiting
- Conditions
- G81.1Spastic hemiplegia
- Registration Number
- DRKS00032429
- Lead Sponsor
- MU Klinikum, Kinderklinik und Poliklinik im Dr. von Haunerschen Kinderspital, Abteilung für Pädiatrische Neurologie, Entwicklungsneurologie und Sozialpädiatrie
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 30
Inclusion Criteria
•Healthy subjects without any chronic disorder
•All participants have to give written informed consent to participate in this study
Exclusion Criteria
•Orthopedic surgery of the lower extremity within the last 12 months
•Contraindications for treatment with magnetic stimulation or MRI imaging:
oDiagnosis of epilepsy
oFerromagnetic implant / biomedical device (e.g., cochlear implant, pacemaker, vagus nerve stimulator, ventriculo-peritoneal shunt)
oPregnancy
oClaustrophobia
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Are there effects on cortical excitability measured by nTMS (changes in MEP-amplitude) after T60 (60 minutes after rNMS stimulation) compared to T0 (baseline)?
- Secondary Outcome Measures
Name Time Method 1. Are there effects on cortical excitability measured by nTMS after T60 compared to T0 (baseline)?<br>2. Are there effects on cortical excitability measured by nTMS at T1 (directly after the rNMS stimulation) and T30 (30 minutes after the rNMS stimulation) compared to T0?