Evaluation of the effect of Ranolazine on patients with slow flow coronary arteries

Phase 2

Recruiting

• Conditions: Coronary slow flow syndrome.; Other forms of angina pectoris; I20.8

• Registration Number: IRCT20220516054874N6
• Lead Sponsor: Mashhad University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 21 November 2022

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 48

Inclusion Criteria

Consent to admission to the study
Age more than 30 years old
Patients who have less than 50% stenosis in each of the 3 main coronary arteries in their coronary angiography and have delayed filling in at least one of the coronary arteries and have slow coronary flow in a corrected TIMI frame count of more than 27 frames per second

Exclusion Criteria

Intolerance or allergy to Ranolazine
History of known congenital heart disease
History of any cardiovascular diseases other than mild coronary atherosclerosis

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Changes in the score of quality of life according to the EuroQol-VAS scale (0-100; 100 is the best quality of life and 0 is the worst quality of life). Timepoint: Before intervention and 1, and 2 months after beginning the intervention. Method of measurement: According to the EuroQol-VAS scale (0-100; 100 is the best quality of life and 0 is the worst quality of life).

Secondary Outcome Measures

Name	Time	Method
Frequent pain during the day. Timepoint: Before intervention and 1, and 2 months after beginning the intervention. Method of measurement: Frequent pain during the day.;Duration of pain in minutes. Timepoint: Before intervention and 1, and 2 months after beginning the intervention. Method of measurement: Duration of pain in minutes.;Pain intensity based on activity according to Canadian Cardiovascular Society (CCS) Grading of Angina Pectoris. Timepoint: Before intervention and 1, and 2 months after beginning the intervention. Method of measurement: According to Canadian Cardiovascular Society (CCS) Grading of Angina Pectoris.