Investigation of the effectiveness of oral lorazepam in managing preoperative dental anxiety in phobic dental patients-A pilot study - Oral lorazepam for managing dental anxiety.
- Conditions
- Pre operative dental anxiety, in phobic dental patients.
- Registration Number
- EUCTR2005-003749-15-GB
- Lead Sponsor
- Merck, Sharp & Dohme-Clinical Pharmacology,Europe
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Authorised-recruitment may be ongoing or finished
- Sex
- All
- Target Recruitment
- 36
Patients referred to the sedation department due to disproportionate dental anxiety
Score 15+ on a Corah dental Anxiety scale
ASA 1&2
Aged 18-50
Able to: attend Newcastle Dental Hospital for treatment; understand the trial; give written consent;take the medication twice daily, in divided doses; avoid driving/working/drinking for the 3 day trial period
Are the trial subjects under 18? no
Number of subjects for this age range:
F.1.2 Adults (18-64 years) yes
F.1.2.1 Number of subjects for this age range
F.1.3 Elderly (>=65 years) no
F.1.3.1 Number of subjects for this age range
Refusal to participate
Corah score <15
Inability to understand the consent/questionnaires
Inability to attend within the time of the trial
Unable to take the medication
Unable to restrain from driving/drinking for the 3 days of the trial.
Study & Design
- Study Type
- Interventional clinical trial of medicinal product
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Main Objective: This pilot study aims to determine the feasibility and the effective dose of oral lorazepam in managing pre operative anxiety in phobic dental patients, scheduled to undergo dental treatment under conscious sedation. ;Secondary Objective: None;Primary end point(s):
- Secondary Outcome Measures
Name Time Method