一项关于声刺激增强慢波睡眠以改善失眠障碍睡眠质量的探索性研究

The sound type will be binaural sound with pure tones (Left: 200Hz; Right: 203Hz; falling within the 0-3Hz slow delta frequency band of EEG, to stimulate super slow waves) for acoustic stimulation. Sound intensity will be calibrated to above the individual auditory threshold (typically 25-50 dB) to avoid arousals. Once the NREM stage 2 sleep is visually detected by the experimenter and stable for at least 30 seconds (At least 6 seconds of slow wave sleep passing at least 75uV amplitude during the 30 second epoch), the sound stimulation will be initiated by the experimenter. The sound stimulus will be delivered during the first two cycles of sleep. The binaural sound will be played through bone transmitted earphones.