Metabolic Changes as a Diagnostic Indicator for Cancer

Completed

• Conditions: Lung Cancer; Breast Cancer
• Interventions: Other: Venous blood sample

• Registration Number: NCT02362776
• Lead Sponsor: Hasselt University

Brief Summary

This study aims to determine whether metabolic changes occur in blood plasma of cancer patients, and whether these changes can be used as a biomarker to detect cancer. These analyses will be done by means of nuclear magnetic resonance (NMR) spectroscopy.

Detailed Description

Not available

Study Timeline

• Study Start: 2009-10
• Primary Completion: 2012-07
• Study Completion: 2012-07
• Study First Submitted: 2013-12-10
• Status Verified: 2015-02
• Study First Submitted QC: 2015-02-09
• Last Update Submitted: 2015-02-09
• Study First Posted: 2015-02-13
• Last Update Posted: 2015-02-13

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 426

Inclusion Criteria

• Diagnosis of breast or lung cancer (new lesion)

Exclusion Criteria

• Not fasted for at least 6 hours
• Plasma glucose concentration ≥ 200 mg/dl
• Intake of medication at the day of investigation
• History/treatment of cancer in the previous 5 years

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
breast cancer patients	Venous blood sample	-
lung cancer patients	Venous blood sample	-
control subjects	Venous blood sample	-

Primary Outcome Measures

Name	Time	Method
Metabolic phenotype of cancer	day 1	Significant metabolic changes in blood between cancer patients \& control subjects

Trial Locations

Locations (2)

Ziekenhuis Oost-Limburg; 🇧🇪 Genk, Limburg, Belgium

Hasselt University; 🇧🇪 Hasselt, Limburg, Belgium