ISRCTN13359367已完成未知
Effect of daily topical administration of TRPM8 agonist in patients with mild to moderate dry eye disease: a single-center randomized double-masked vehicle-controlled study
Chonnam National University Medical School and Hospital0 个研究点目标入组 40 人开始时间: 2015年9月2日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 40
研究概览
简要总结
- 2017 results in https://www.ncbi.nlm.nih.gov/pubmed/28651550 (added 23/01/2019) 2. 2018 results in https://www.ncbi.nlm.nih.gov/pubmed/30445735 (added 23/01/2019)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Dry eye symptoms for more than 3 months despite the use of artificial tears
- •2. Low tear film break-up time (TBUT) (= 7 seconds)
- •3. Low Schirmer score (= 10 mm/5 min)
- •4. Presence of corneal and conjunctival epithelial damage
排除标准
- •1. History of any ocular disease other than DED
- •2. Meibomian gland dysfunction
- •3. Contact lens use
- •4. Ocular trauma or surgeries
- •5. Presence of an uncontrolled systemic disease that could affect ocular surface condition
- •6. Punctual plugs
- •7. Used any eye drops other than artificial tears
- •8. Used any systemic medication that can cause dry eye
- •9. Pregnant
研究者
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