ISRCTN24802609已完成未知
Effect of topical administration of TRPM8 agonist in patients with dry eye disease: a single-center randomized double-masked vehicle-controlled study
Chonnam National University Medical School and Hospital0 个研究点目标入组 60 人开始时间: 2015年3月21日最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 已完成
- 发起方
- 入组人数
- 60
研究概览
简要总结
2017 results in https://pubmed.ncbi.nlm.nih.gov/28651550/ (added 25/06/2020)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- All
入选标准
- •1. Dry eye symptoms for more than 3 months despite the use of artificial tears
- •2. Low tear film break-up time (TBUT) (= 7 seconds)
- •3. Low Schirmer score (= 10 mm/5 min)
- •4. Presence of corneal and conjunctival epithelial damage
排除标准
- •1. History of any ocular disease other than DED
- •2. Meibomian gland dysfunction
- •3. Contact lens use
- •4. Ocular trauma or surgeries
- •5. Presence of an uncontrolled systemic disease that could affect ocular surface condition
- •6. Punctual plugs
- •7. Used any eye drops other than artificial tears
- •8. Used any systemic medication that can cause dry eye
- •9. Pregnant
研究者
相似试验
已完成
不适用
Ectopic activation of TRPM8 with a newly-developed agonist relieves dry-eye symptomsEye DiseasesOther disorders of lacrimal glandDry eyeISRCTN13359367Chonnam National University Medical School and Hospital40
已完成
2 期
TRPM8 in Acute Ischemic Stroke by Topical MentholIschemic StrokeNCT05877079Taipei Medical University Hospital60
已完成
不适用
Investigation of a New Human Model for ItchItchNCT04711044Aalborg University20
已完成
4 期
Effect of 8 weeks oral pentaerithrityltetranitrate on endothelial dysfunction in patients with coronary artery disease: a prospective, randomized, double-blind, placebo-controlled, monocentric clinical trial of phase IVCoronary artery diseaseCirculatory SystemISRCTN14741769Johannes Gutenberg University of Mainz (Germany)80
已完成
1 期
Intradermal Injection of Anti-CTLA-4 in Patients With Stage I/II MelanomaCutaneous MelanomaNCT04274816A.J.M. van den Eertwegh13