The effect of Olibanum (Boswellia serrata) gel on clinical symptoms in patients with Osteoarthritis of the knee

Phase 3

Conditions: Knee osteoarthritis.
Osteoarthritis of knee

Registration Number: IRCT20201210049670N1

Lead Sponsor: Shahid Beheshti University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 86

Inclusion Criteria

Patients more than 40 and less than 70
Patients with a diagnosis of osteoarthritis grade 1,2,3
knee pain
Morning knee dryness less than 30 minutes
Crepitus
Osteophyte in radiography

Exclusion Criteria

History of rheumatoid arthritis, gout, CPPD
Existence of uncontrolled cardiovascular disease
Proven malignancy
Severe kidney disease (creatinine above 3 Mg /Dl)
Receive oral corticosteroids 4 weeks in advance
Take NSAIDs with a dose of more than 50 mg daily except aspirin and acetaminophen up to a dose of more than 650 mg daily
Intra-articular administration of the drug in the previous three months
The patient's unwillingness or ability to fill in the text of the questionnaire used in the study
The patient's unwillingness to continue participating in the study

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
BMI. Timepoint: The beginning of the study. Method of measurement: Weighing with scales and height with meters.;KOOS questionnaire PAIN. Timepoint: At the beginning of the study and after 4 weeks. Method of measurement: Based on a questionnaire filled out by the patient himself.;KOOS questionnaire Light daily activity. Timepoint: At the beginning of the study and after 4 weeks. Method of measurement: Based on a questionnaire filled out by the patient himself.;KOOS questionnaire Intense and sports activity. Timepoint: At the beginning of the study and after 4 weeks. Method of measurement: Based on a questionnaire filled out by the patient himself.;Quality of Life. Timepoint: At the beginning of the study and after 4 weeks. Method of measurement: Based on a questionnaire filled out by the patient himself.;Acetaminophen intake per day. Timepoint: At the beginning of the study and after 4 weeks. Method of measurement: Based on biography.

Secondary Outcome Measures