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A clinical trial to study the effects of pre operative tablet melatonin in patients undergoing infra umbilical surgeries under spinal anaesthesia.

Completed
Conditions
Unspecified abdominal hernia withobstruction, without gangrene,
Registration Number
CTRI/2018/08/015192
Lead Sponsor
Sagar Srinivas K
Brief Summary

This is a randomized, double blind, parallel group trial comparing the efficacy of preoperative oral melatonin 3mg on postoperative pain in patients undergoing infra-umbilical surgeries under subarachnoid block. It will be conducted in VIctoria hospital, Bangalore. The primary outcome measure is post-operative pain in first 24 hours. The secondary outcomes are to assess the peri-operative sedation and anxiolytic effects of oral melatonin 3mg.

Detailed Description

Not available

Recruitment & Eligibility

Status
Completed
Sex
All
Target Recruitment
70
Inclusion Criteria
  • Patients who have given written informed consent.
  • Patients with ASA grade I & II.
  • Patients scheduled for elective infra-umbilical surgeries under subarachnoid block.
Exclusion Criteria
  • Patients refusing to participate in the study.
  • Patients with history of psychiatric disorders on antipsychotic drugs.
  • Patients with history of sleep disorders.
  • Patients on anticoagulants.
  • Patients with hypertension, type2 DM, IHD.
  • Pregnant women.
  • Contraindication to spinal anaesthesia.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Postoperative pain measured using VAS scorePostoperative 24 hours
Secondary Outcome Measures
NameTimeMethod
Anxiety measured using HAM-A scalePeri-operatively upto 24 hours after surgery

Trial Locations

Locations (1)

Victoria Hospital

🇮🇳

Bangalore, KARNATAKA, India

Victoria Hospital
🇮🇳Bangalore, KARNATAKA, India
Sagar Srinivas K
Principal investigator
9844265261
sagarsrinivas91@gmail.com

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