Metabolic Study of Concentric and Eccentric Muscle Training
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lipid Metabolism
- Sponsor
- Vorarlberg Institute for Vascular Investigation and Treatment
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- Metabolic and anti-inflammatory effects induced by eccentric muscle exercise.
- Status
- Completed
- Last Updated
- 19 years ago
Overview
Brief Summary
The purpose of this study is to evaluate the metabolic and anti-inflammatory effects of eccentric endurance exercise and to compare them with those of concentric exercise in healthy sedentary individuals.
Detailed Description
Physical exercise decreases the risk of obesity, diabetes mellitus, and cardiovascular disease. Skeletal muscle can be exercised by two ways: Concentric contraction is defined as active shortening of muscles, e.g. by stepping upwards, whereas eccentric muscle contraction is defined as active resistance to stretching, e.g. by stepping downwards. Although the effects of exercise (i.e. the combination of concentric and eccentric muscle contraction) on metabolic parameters have been extensively investigated, there are no data on the specific metabolic effects of concentric versus those of eccentric muscle work in humans. Comparison(s): Metabolic and anti-inflammatory effects of eccentric endurance exercise (i.e. stepping upwards), compared to metabolic and anti-inflammatory effects of concentric exercise (i.e. stepping downwards).
Investigators
Eligibility Criteria
Inclusion Criteria
- •healthy men and women
- •age over 30 years
Exclusion Criteria
- •previous systematic endurance training (≥3 times per week ≥30 min)
- •body mass index \>30 kg/m2
- •heavy smoking (\>20 cigarettes per day)
- •regular alcohol consumption \>60g per day
- •established musculoskeletal disease
- •history of cardiovascular disease
- •diabetes mellitus
- •unwillingness to stay in the area for the whole study period
Outcomes
Primary Outcomes
Metabolic and anti-inflammatory effects induced by eccentric muscle exercise.
Secondary Outcomes
- Metabolic and anti-inflammatory effects induced by concentric muscle exercise.