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Clinical Trials/NCT06331221
NCT06331221
Completed
Not Applicable

Effects of Different Concentric and Eccentric Muscle Fatigue Protocols on the Knee Joint Position Sense: a Randomized Controlled Crossover Trial

Universidade do Porto1 site in 1 country22 target enrollmentNovember 2, 2023
ConditionsHealthy

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Healthy
Sponsor
Universidade do Porto
Enrollment
22
Locations
1
Primary Endpoint
Absolute angular error
Status
Completed
Last Updated
last year

Overview

Brief Summary

The aim of this study was to investigate the effects of different concentric and eccentric muscle fatigue protocols on the knee joint position sense of healthy individuals.

Detailed Description

A randomized controlled crossover trial will be conducted at a biomechanics laboratory with healthy males. All participants will perform with a washout period of 1 week: a control condition (5-minute rest) and 4 local muscle fatigue protocols (concentric of quadriceps; concentric of hamstrings; eccentric of quadriceps; eccentric of hamstrings) in an isokinetic dynamometer at 30º/s. Three maximum voluntary isometric contractions (MVIC) of quadriceps and hamstrings will also be assessed in the beginning of all conditions. Knee joint position sense will be assessed before and immediately after the fatigue protocols/control condition, through active concentric and eccentric positionings/repositionings, in sitting and prone positions, to a target range of 45º of knee flexion in an isokinetic dynamometer. Surface electromyography electrodes will also be placed on the vastus lateralis and biceps femoris during all procedures.

Registry
clinicaltrials.gov
Start Date
November 2, 2023
End Date
May 15, 2024
Last Updated
last year
Study Type
Interventional
Study Design
Crossover
Sex
Male

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • males aged between 18 and 30 years;
  • without current or previous knee pathology or surgery;
  • with a low or moderate physical activity level, according to the International Physical Activity Questionnaire;
  • normal Body Mass Index (under 24.9 kg/m2), according to the World Health Organization.

Exclusion Criteria

  • those with cardiorespiratory, neurological or vestibular pathologies;
  • with positive knee integrity tests (anterior drawer, Lachman's test, posterior drawer; valgus and varus stress testes); and
  • those taking any medication that can affect motor control (sedatives, anxiolytics, antibiotics, analgesics, NSAIDs or myorelaxants).

Outcomes

Primary Outcomes

Absolute angular error

Time Frame: Change from Baseline (Before) to Immediately after interventions or control (After)

The absolute value of the difference between the target range and the achieved range

Relative angular error

Time Frame: Change from Baseline (Before) to Immediately after interventions or control (After)

The arithmetic difference between the target range and the range achieved

Variable angular error

Time Frame: Change from Baseline (Before) to Immediately after interventions or control (After)

The standard deviation of the 3 repositionings

Study Sites (1)

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