Rhizophora mangle (red mango) cream on skin wound healing
Not Applicable
Recruiting
- Conditions
- cutaneous woundL98.8
- Registration Number
- RBR-37hrf2
- Lead Sponsor
- Centro de Ciencias da Saúde da Universidade Federal de Pernambuco
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- Not specified
Inclusion Criteria
Volunteers who will undergo plastic surgery of the upper eyelids at the Santa Luzia Foundation; Both genders; Age between 18 and 65 years; Normal preoperative blood and cardiac tests
Exclusion Criteria
Volunteer smokers; Diagnosis of infection in the eyelids; Diagnosis of cancer; Diagnosis of diabetes; Diagnosis of renal, hepatic, hematological or immune pathologies; Diagnosis of obesity; Use of immunosuppressive or corticoid medications
Study & Design
- Study Type
- Intervention
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Improvement of the skin wound healing process of the group using Rhizophora mangle cream compared to the group using the dexpanthenol cream evaluated by morphometric and histomorphometric examination in data collected 1 week after the intervention
- Secondary Outcome Measures
Name Time Method Major retraction of the wound in the Rhizophora mangle cream group evaluated by morphometry (pachymeter for measurement) 1 week after the intervention. The degree of retraction of cutaneous wounds will be calculated from the equation formulated by Prata et al. (1988): A = pi . R . r<br>Greater area of wound reepithelialization of the group treated with Rhizophora mangle cream evaluated by calculating the distance between the epithelia in the healing, performed through the software Pannoramic Viewer version 1.15.4 year 2014, 1 week after the intervention.<br>Increased number of wound fibroblasts in the group using Rhizophora mangle cream evaluated by counting in a histological study 1 week after the intervention