Resection Location of Rectum in Laparoscopic Surgery for Slow Transit Constipation

Not Applicable

• Conditions: Constipation; Slow Transit
• Interventions: Procedure: Laparoscopic total colectomy + low resection of rectum; Procedure: Laparoscopic total colectomy + High resection of rectum

• Registration Number: NCT04525248
• Lead Sponsor: Shanghai Minimally Invasive Surgery Center

Brief Summary

Study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum

Detailed Description

The investigators are going to study the recurrence rate of constipation after laparoscopic total colectomy with high resection or low resection of rectum. High resection is defined as resection at 12\~15cm from anus and low resection as 6\~8cm.

Study Timeline

• Status Verified: 2020-08
• Study First Submitted: 2020-08-18
• Study First Submitted QC: 2020-08-23
• Last Update Submitted: 2020-08-23
• Study First Posted: 2020-08-25
• Last Update Posted: 2020-08-25
• Study Start: 2020-09-01
• Primary Completion: 2023-08-01
• Study Completion: 2024-08-01

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 78

Inclusion Criteria

• Diagnosed as constipation according to Rome IV criteria
• Diagnosed as slow transit constipation
• With more than 2 years' drug treatment or with outlet obstruction or with surgical history

Exclusion Criteria

• Colon cancer
• History of colon, rectum, anus surgery
• With severe cardio, renal, neural disease
• Pregnant patients

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Low resection	Laparoscopic total colectomy + low resection of rectum	Laparoscopic total colectomy + Low resection of rectum
High resection	Laparoscopic total colectomy + High resection of rectum	Laparoscopic total colectomy + High resection of rectum

Primary Outcome Measures

Name	Time	Method
1-year recurrence rate of constipation	1 year	1-year recurrence rate of constipation

Secondary Outcome Measures

Name	Time	Method
perioperative complications	1 year	perioperative complications
1-year rate of diarrhea	1 year	1-year rate of diarrhea