Bilateral Lateral OFC rTMS in Obsessive Compulsive Disorder
- Conditions
- Obsessive-Compulsive Disorder
- Registration Number
- NCT04934007
- Lead Sponsor
- Centre Hospitalier Henri Laborit
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 136
Inclusion Criteria:<br><br> - Age: Participants will be both males and females, 18-65 years of age included.<br><br> - diagnosis of OCD<br><br> - all the patients must have failed to respond to at least two different<br> pharmacological treatment used for at least 6 weeks<br><br> - Affiliation to a social security system (recipient or assignee),<br><br> - Signed written inform consent form<br><br>Exclusion Criteria:<br><br> - The exclusion criteria are a diagnosis of another psychiatric disorder (except for<br> anxious disorders), a diagnosis of a significant active medical illness, pregnancy<br> or other neurological illness<br><br> - In accordance with the safety criteria for rTMS, patients with a history of seizure<br> or bearing pacemakers, mobile metal implants, implanted medical pumps, or metal<br> clips placed inside the skull will also be excluded<br><br> - The patients won't be allowed to change their medication during the trial. The<br> treatment must be stable at least 3 week before day 0.<br><br> - Female subject who is pregnant, or of child-bearing age, sexually active and not<br> using reliable contraception or who is nursing,<br><br> - Patient under curators<br><br> - Patient hospitalized under duress<br><br> - Patient unable to give his or hers informed consent
Not provided
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Yale Brown Obsessive Compulsive Scale score
- Secondary Outcome Measures
Name Time Method Yale Brown Obsessive Compulsive Scale;general assessement functioning (GAF);general assessement functioning (GAF);Clinical Global Impression (CGI);Clinical Global Impression (CGI);Adverse events linked to the rTMS treatment