Sodium Bicarbonate versus Saline for the prevention of Contrast Induced Nephropathy in patients undergoing angiography

Recruiting

• Conditions: contrast induced nephropathy; contrast medium induced nephropathy; 10029149; 10003216

• Registration Number: NL-OMON37953
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 11 June 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 346

Inclusion Criteria

- patients undergoing angiography with intra arterial contrast administration
- eGFR (estimated glomerular filtration rate) < 60 ml/min

Exclusion Criteria

- age < 18 years
- heamodynamic instability
- pregnancy
- allergy for contrast media

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>• mean rise in serum creatinine 2-4 days after angiography</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>• CIN defined as an increase in serum creatinine > 25% or > 44 µmol/l after 2-4<br />days;<br />• CIN defined as an increase in serum creatinine > 25% or > 44 µmol/l after 2<br />months;<br />• Indication for dialysis due too CIN;<br />• Congestive heart failure due to rapid volume expansion with an indication for<br />treatment with diuretics.</p>