Chronic obstructive pulmonary disease (COPD) as syndrome of accelerated aging

Completed

• Conditions: Chronic obstructive pulmonary disease (COPD); Respiratory; Other chronic obstructive pulmonary disease

• Registration Number: ISRCTN86049077
• Lead Sponsor: Dutch Asthma Foundation (Netherlands)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2010-05-18
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 600

Inclusion Criteria

COPD patients:
1. Diagnosis of COPD according to the American Thoracic Society (ATS) Global Initiative for Chronic Obstructive Lung Disease (GOLD) guidelines (forced expiratory volume in one second [FEV1] less than 80% predicted and FEV1/forced vital capacity [FVC] less than 70% and less than 10% predicted improvement in FEV1 after ?Ò2-agonist inhalation
2. Both male and female, aged from 50 to 75 years
3. No respiratory tract infection or exacerbation of the disease for less than 4 weeks before the study
4. Capable of providing informed consent

Healthy subjects:
1. Healthy subjects as judged by a physician
2. Without diagnosed COPD or any other described co-morbidity/chronic disease
3. Both male and female, aged from 50 to 75 years

Exclusion Criteria

COPD patients:
1. Any kind of carcinogenic pathology less than 5 years before study participation
2. Participation in any other studies involving investigational or marketed products concomitantly or less than 4 weeks prior to entry into the study

Healthy subjects:
1. Investigator's uncertainty about the willingness or ability of the subject to comply with the protocol requirements
2. Participation in any other study involving investigational or marketed products concomitantly or within two weeks prior to entry into the study

Study & Design

• Study Type: Observational
• Study Design: Not specified