Effect of irrigation with ozonized water during ultrasonic scaling in the management of periodontitis: A randomized controlled clinical trial.
试验速览
- 阶段
- Phase 3 4
- 状态
- 尚未招募
- 发起方
- 入组人数
- 60
- 试验地点
- 1
研究概览
简要总结
This randomized controlled clinical trial investigates the efficacy of ozonized water irrigation compared to normal saline during ultrasonic scaling in the management of periodontitis. The study aims to evaluate clinical improvements in periodontal parameters specifically probing pocket depth and clinical attachment level as well as biochemical changes reflected by salivary interleukin 1 beta IL 1 beta levels. Conducted in a tertiary care setting over one year the trial includes 60 participants aged 30 to 60 years diagnosed with Stage III periodontitis. Subjects are randomly allocated into two groups Group A receives ozonized water irrigation and Group B receives normal saline irrigation during scaling. Clinical and biochemical assessments are performed both before and after treatment. The study hypothesizes that ozonized water irrigation provides superior improvement in periodontal health and exhibits enhanced anti inflammatory effects compared to normal
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 30.00 Year(s) 至 60.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients with Stage III periodontitis (diagnosed according to 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions)31 Patients with minimum of 20 remaining teeth Subjects with PPD greater than or equal to 5mm in at least one site /quadrant.
- •Subjects who had not received periodontal therapy within the last 6 months.
- •Those who were willing to participate in the study.
排除标准
- •Patients with Stage III periodontitis (diagnosed according to 2017 world workshop on the classification of periodontal and peri-implant diseases and conditions)31 Patients with minimum of 20 remaining teeth Subjects with PPD greater than or equal to 5mm in at least one site /quadrant.
- •Subjects who had not received periodontal therapy within the last 6 months.
- •Those who were willing to participate in the study.
研究者
Dr Niranjana J Mohan
Department of Periodontics, PMS College of Dental Science and Research,