Comparison of effect of three methods of Rectal Naproxen Suppository, Isosorbide Dinitrate tablets and concurrent use of Rectal Naproxen Suppository with Isosorbide Dinitrate tablets in Prevention of Post- Endoscopic Retrograde Cholangio Pancreatography (ERCP) pancreatitis in patients

Phase 3

• Conditions: Post ERCP Pancreatitis.; Other Acute Pancreatitis

• Registration Number: IRCT201409251155N22
• Lead Sponsor: Vice chancellor for research of Guilan University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 585

Inclusion Criteria

All patients over 18 years who were referred to Razi Hospital of Rasht for ERCP. Exclusion criteria: Acute pancreatitis in the last two weeks; history of chronic pancreatitis; a history of previous sphincterotomy; NSAID or Nitrate usage in a week prior and contraindication for NSAID or Nitrate usage like renal failure; recent Peptic Ulcer disease with recent GI Bleeding; Hypotension and Hypersensitivity to recent Each of the two drugs and lack of satisfaction of participate in this study.

Exclusion Criteria

Not provided

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Serum levels of Amylase. Timepoint: Two hours after ERCP. Method of measurement: Laboratory Kit.;Symptoms of nausea, vomiting and abdominal pain. Timepoint: 2 hours after ERCP. Method of measurement: Observations with check list.

Secondary Outcome Measures

Name	Time	Method
Serum levels of Amylase. Timepoint: 24 hours after ERCP. Method of measurement: Laboratory Kit.;Symptoms of nausea, vomiting and abdominal pain. Timepoint: 24 hours after ERCP. Method of measurement: Observation with check list.