Comparison the effects of the isosorbide mononitrate with misoprostol and misoprostol with placebo for cervical ripening in induction of labour in 41 week pregnancies.
Not Applicable
- Conditions
- prolonged pregnancy.Prolonged pregnancy
- Registration Number
- IRCT2016022426745N1
- Lead Sponsor
- Vice Chancellor for Research, Mashhad university of medical sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- Female
- Target Recruitment
- 186
Inclusion Criteria
The inclusion criteria are first pregnancies aged more than 41 weeks based on the sonography; with single; normal fetus; and cephalic presentation with no complication and before induction bishop score less than 6.
Exclusion criteria include known allergy for prostaglandins or mifepristone; any contraindication for induction (such as uterine scar); contraindications for mifepristone administration (like adrenal, renal or liver disease); major cephalopelvic disproportion; abnormal stress test; vaginal bleeding and sever oligohydramnios.
Exclusion Criteria
Not provided
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Fetal heart rate. Timepoint: each 30 minutes. Method of measurement: quantitative with sonography.
- Secondary Outcome Measures
Name Time Method Maternal blood pressure. Timepoint: each 30 minutes. Method of measurement: quantitative with pressure indicator.