Effect of misoprostol plus isosorbide mononitrate and misoprostol plus placebo in induction of second trimester abortio

Not Applicable

• Conditions: Termination of pregnancy.; Pregnancy with abortive outcome

• Registration Number: IRCT20100525004025N5
• Lead Sponsor: Research deputy Kermanshah University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Last Update Posted: 22 February 2018

Recruitment & Eligibility

• Status: Complete
• Sex: Female
• Target Recruitment: 54

Inclusion Criteria

Gestational age 22-13 weeks can be a condition for entering the study.
nulliparous Can be a condition for entering the study.
Multiparous to parity 5 Can be a condition for entering the study.
singleton pregnancy can be a condition for entering the study.

Exclusion Criteria

Women with contra indication of misoprostol (active Cardiac-pulmonary disease, Placenta Previa, history of 2 or more previous cesarean section, or history of major uterine surgeries such as myomectomy and uterine reconstruction surgery)Conditions for not admitting to study.
Women with contraindication of Isosorbide mono nitrate (IMN) (sensitivity to nitrates, hypotension, hypovolemia, heart disease, significant anemia Hb below 7 gr / dl and closed angle glaucoma )Conditions for not admitting to study.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The abortion rate is 12 hours. Timepoint: 12 hours later intervention. Method of measurement: View the disposal of pregnancy products.;The abortion rate is 24-12 hours. Timepoint: Abortion after 12 hours to 24 hours of intervention. Method of measurement: View the disposal of pregnancy products.;Abortion rate after 24 hours. Timepoint: In the 24th hour of the intervention. Method of measurement: View the disposal of pregnancy products.