Aripiprazole Treatment of Prodromal Patients
Overview
- Phase
- Phase 2
- Intervention
- Not specified
- Conditions
- Schizophrenia
- Sponsor
- Yale University
- Enrollment
- 15
- Locations
- 2
- Primary Endpoint
- Total Score of the Scale Of Prodromal Symptoms
- Status
- Completed
- Last Updated
- 11 years ago
Overview
Brief Summary
We hypothesize that symptoms will improve in patients who meet diagnostic criteria for the schizophrenia prodrome when they are prescribed aripiprazole.
Detailed Description
This is an 8 week trial with extension for responders out to one year. All patients receive active medication; there is no placebo. Patients must meet criteria for the schizophrenia prodrome according to the Structured Interview for Prodromal Syndromes. Patients receive counseling as well. All counseling and medication are free of charge.
Investigators
Eligibility Criteria
Inclusion Criteria
- •age 13 to 40 meet criteria for the prodrome for schizophrenia
Exclusion Criteria
- •history of psychosis
Outcomes
Primary Outcomes
Total Score of the Scale Of Prodromal Symptoms
Time Frame: 8 weeks
This is a 19-item scale with items scores 0-6. Treatment response is defined as all 5 Scale of Prodromal Syndromes positive symtpom items being rate below the prodromal range (\< or equal to 2).