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Clinical Trials/NCT05342324
NCT05342324
Completed
Not Applicable

Optical Coherence Tomography Angiography in Choroidal Osteoma: a Quantitative Evaluation of Choriocapillary Vessel Density

Federico II University1 site in 1 country28 target enrollmentJune 1, 2015

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Choroidal Osteoma, Bilateral
Sponsor
Federico II University
Enrollment
28
Locations
1
Primary Endpoint
Study of vessel density of the choriocapillary in patients affected by choroidal osteoma .
Status
Completed
Last Updated
4 years ago

Overview

Brief Summary

This study evaluates the vessel density of choriocapillary vascular network in eyes affected by choroidal osteoma and in eyes complicated by choroidal neovascularization, using optical coherence tomography angiography.

Detailed Description

The choroidal osteoma is a rare benign tumor of choroid, it is bilateral in 10%-25% of cases, affecting usually young women. Previous studies evaluated the morphologic characteristics of tumor-related vasculatures, described as a seafun vascular networks, but none focused on study of vessel density of coriocapillary. The aim of this study is to investigate the potential role of the optical coherence tomography angiography (OCTA) in evaluating the choriocapillary vessel density in order to individuate the changes of this vascular network that may influence the onset of choroidal neovasculariztion. Therefore, OCTA could be useful in the clinical management of the choroidal osteoma

Registry
clinicaltrials.gov
Start Date
June 1, 2015
End Date
January 31, 2022
Last Updated
4 years ago
Study Type
Observational
Sex
All

Investigators

Sponsor
Federico II University
Responsible Party
Principal Investigator
Principal Investigator

Gilda Cennamo

Principal Investigator

Federico II University

Eligibility Criteria

Inclusion Criteria

  • age older than 50 years
  • diagnosis of choroidal osteoma
  • absence of history of vitreoretinal and vascular retinal diseases

Exclusion Criteria

  • age younger than 50 years
  • no diagnosis of choroidal osteoma
  • presence of history of vitreoretinal and vascular retinal diseases

Outcomes

Primary Outcomes

Study of vessel density of the choriocapillary in patients affected by choroidal osteoma .

Time Frame: 7 years

To evaluate the role of optical coherence tomography angiography in evaluating the features of the choriocapillary, using optical coherence tomography angiography (OCTA) in patients with choroidal osteoma and in patients with choroidal osteoma complicated by choroidal neovascularization. The parameter analyzed by OCTA was the vessel density of choriocapillary (percent)

Study Sites (1)

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